The amide derived from isovaleric acid, it is a colourless solid.
2.
This odor is caused by the buildup of a compound called isovaleric acid in affected individuals.
3.
Those cigarettes also include such not-so-cookieish items as glycerol, propylene glycol, isovaleric acid, hexanoic acid and 3-methylpntanoic acid.
4.
As a result, isovaleric acid and related compounds build up to toxic levels, damaging the brain and nervous system.
5.
Lastly, a post-NRPS modification happens in the free hydroxyl group from the second isovaleric acid, adding an acetyl group.
6.
Isovaleric acid is seen as the primary cause of the flavors added to wine caused by " Brettanomyces " yeasts.
7.
The yeast " Brettanomyces " produces an array of metabolites when growing in wine, some of which are volatile isovaleric acid.
8.
Aust said isovaleric acid is used in varying amounts to create an odor " that is very much like dirty socks ."
9.
The final genes hctG and hctH probably encode two P450 that oxidize the side chain of both isovaleric acids ( Figure 1D ).
10.
HctE consists of a bi-modular NRPS, of which the first module incorporates an isovaleric acid and the second module incorporates a heterocyclic cysteine.
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